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System for the Preparation of Autologous
Platelet-Rich Fibrin Matrix (PRFM)

About the SELPHYL® PRFM System

  • PRFM Scaffold Protects Platelets
  • Platelets Last Up to 7 Days *
  • Easy to Use and Reproducible
  • Full Training and Continued Support for Staff

As Seen In

The New York TimesABCCBS

The SELPHYL® System
What Items are Included in Your PRFM Kit?

The SELPHYL® System quickly and safely prepares Platelet-rich Fibrin Matrix (PRFM) from a small blood sample, eliminating contamination and operator variability. It converts PRP into PRFM, creating a protective scaffold for platelets.

SELPHYL® PRFM is the next generation of PRP.

Selphyl Kit Elements

SELPHYL® PRFM is used by physicians for various applications. The simple, 20-minute procedure may yield results after one treatment, though additional sessions are often recommended. Your doctor will tailor the best approach for you.

SELPHYL Test Tube with Platelet and Fibrin

The Next Generation PRP

SELPHYL Aesthetic Centrifuge
  • Simple, 20-minute procedure
  • Utilized for various medical applications
  • Enhances the body's natural healing capabilities
  • Produces Platelet-rich Fibrin Matrix (PRFM)
  • Localizes platelets at injury sites for sustained healing
  • Promotes growth factor release and stem cell migration
  • Customizable treatment plans tailored by physicians
  • Typically requires multiple sessions for optimal results

How is SELPHYL® PRFM Different from PRP?

Traditional
PRP

Traditional PRP platelets

SELPHYL®
PRFM

SELPHYL PRFM platelets in fibrin matrix
Learn More About The SELPHYL System

Growth Factor Total (pg)

Traditional PRP growth factor graph

Hours Post Blood Draw

Growth Factor Total (pg)

SELPHYL PRFM growth factor graph

Hours Post Blood Draw

Traditional PRPSELPHYL® PRFM
Platelet-Rich Fibrin Matrix
Platelets Release Growth Factors Up to 7 Days *
Fully Closed System
Training and Support for Staff
SELPHYL® Clinical Papers Available

The Science Behind SELPHYL®
Platelets Release Growth Factors

Platelets growth factors diagram

As soon as SELPHYL® - prepared PRFM is administered, growth factors are released through the formation of a three dimensional cross-linked fibrin matrix which is essential to the platelet plug as it serves as a binding site for both platelets and growth factors allowing their sustained release.

This scaffolding (fibrin matrix) localizes the growth factors increasing their concentration at the desired location and guiding tissue regeneration. Studies have shown that platelet growth factors are released for up to seven days, supporting collagen production and increased vascularization, which results in overall skin improvements.

Growth factors total over hours post blood draw