
The SELPHYL® System:
The Next Generation
About the SELPHYL® PRFM System
Platelet-Rich Fibrin Matrix (PRFM)
Converts Traditional PRP in PRFM
- Platelets Last Up to 7 Days *
(VS only Hours with Traditional PRP) - Easy to Use and Reproducible
- Full Training and Continued Support for Staff
As Seen In


The SELPHYL® System quickly and safely prepares Platelet-rich Fibrin Matrix (PRFM) from a small blood sample, eliminating contamination and operator variability. It converts PRP into PRFM, creating a protective scaffold for platelets.
SELPHYL® PRFM is the next generation of PRP.

The Strength of Platelets
Platelets and other blood components migrate to injury sites, releasing growth factors that initiate and promote healing. Concentrating platelets at these sites can enhance the body's natural healing capacity.

The Key Advantages & Benefits Include:
- Superior technology
- A visual guide to quality
- Completely closed system
- Ultrapure PRFM
- Operator independent
- Fibrin matrix scaffold
- Viable platelets
- Sustained platelet growth factor release for days
- Extensive safety profile
- Over 150k patients treated

What is Platelet-Rich Plasma (PRP)?
PRP is plasma with a platelet concentration about twice that of normal blood. It should exclude red and white blood cells, which can cause inflammation. Some kits with high platelet counts may also contain these cells, reducing effectiveness. PRP should be golden, not pink or red, indicating purity from RBC contamination.

How is SELPHYL® PRFM Different from PRP?
Traditional
PRP

SELPHYL®
PRFM

Growth Factor Total (pg)

Hours Post Blood Draw
Growth Factor Total (pg)

Hours Post Blood Draw
The Science Behind SELPHYL®
Platelets Release Growth Factors

As soon as SELPHYL® - prepared PRFM is administered, growth factors are released through the formation of a three dimensional cross-linked fibrin matrix which is essential to the platelet plug as it serves as a binding site for both platelets and growth factors allowing their sustained release.
This scaffolding (fibrin matrix) localizes the growth factors increasing their concentration at the desired location and guiding tissue regeneration. Studies have shown that platelet growth factors are released for up to seven days, supporting collagen production and increased vascularization, which results in overall skin improvements.




