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The SELPHYL® System:
The Next Generation

About the SELPHYL® PRFM System

Platelet-Rich Fibrin Matrix (PRFM)

Converts Traditional PRP in PRFM

  • Platelets Last Up to 7 Days *
    (VS only Hours with Traditional PRP)
  • Easy to Use and Reproducible
  • Full Training and Continued Support for Staff

As Seen In

The New York TimesABCCBS

The SELPHYL® System quickly and safely prepares Platelet-rich Fibrin Matrix (PRFM) from a small blood sample, eliminating contamination and operator variability. It converts PRP into PRFM, creating a protective scaffold for platelets.

SELPHYL® PRFM is the next generation of PRP.

SELPHYL PRFM Kit Components

The Strength of Platelets

Platelets and other blood components migrate to injury sites, releasing growth factors that initiate and promote healing. Concentrating platelets at these sites can enhance the body's natural healing capacity.

Model

The Key Advantages & Benefits Include:

  • Superior technology
  • A visual guide to quality
  • Completely closed system
  • Ultrapure PRFM
  • Operator independent
  • Fibrin matrix scaffold
  • Viable platelets
  • Sustained platelet growth factor release for days
  • Extensive safety profile
  • Over 150k patients treated
SELPHYL test tube

What is Platelet-Rich Plasma (PRP)?

PRP is plasma with a platelet concentration about twice that of normal blood. It should exclude red and white blood cells, which can cause inflammation. Some kits with high platelet counts may also contain these cells, reducing effectiveness. PRP should be golden, not pink or red, indicating purity from RBC contamination.

Platelet-Rich Plasma

How is SELPHYL® PRFM Different from PRP?

Traditional
PRP

Traditional PRP platelets

SELPHYL®
PRFM

SELPHYL PRFM platelets in fibrin matrix
Learn More About The SELPHYL System

Growth Factor Total (pg)

Traditional PRP growth factor graph

Hours Post Blood Draw

Growth Factor Total (pg)

SELPHYL PRFM growth factor graph

Hours Post Blood Draw

Traditional PRPSELPHYL® PRFM
Platelet-Rich Fibrin Matrix
Platelets Release Growth Factors Up to 7 Days *
Fully Closed System
Training and Support for Staff
SELPHYL® Clinical Papers Available

The Science Behind SELPHYL®
Platelets Release Growth Factors

Platelets growth factors diagram

As soon as SELPHYL® - prepared PRFM is administered, growth factors are released through the formation of a three dimensional cross-linked fibrin matrix which is essential to the platelet plug as it serves as a binding site for both platelets and growth factors allowing their sustained release.

This scaffolding (fibrin matrix) localizes the growth factors increasing their concentration at the desired location and guiding tissue regeneration. Studies have shown that platelet growth factors are released for up to seven days, supporting collagen production and increased vascularization, which results in overall skin improvements.

Growth factors total over hours post blood draw