top of page

What Is a Vampire Facial, and Who Can Benefit From It?

The term "vampire facial" has become a ubiquitous colloquialism referring to a specific cosmetic procedure known officially as platelet-rich plasma (PRP) facial therapy. This procedure harnesses the healing components in the patient's own blood. At its core, what is a vampire facial? It essentially involves the extraction of a patient's own blood, the isolation of plasma rich in platelets, and the subsequent re-administration of this concentrated plasma to the facial tissue. [1]

What is vampire facial - Selphyl

PRP is built on the understanding that platelets, which are crucial elements in blood for their role in clotting and healing processes, contain growth factors. These factors are believed to support the health of skin cells. When these platelets are extracted, centrifuged, and then reintroduced into the skin, PRP facials are said to aid in the acceleration of healing and an increase in new collagen and production, leading to improved skin appearance.

Throughout the last ten years, the name vampire facial treatment has journeyed through waves of popularity and skepticism, as portrayed by popular media. Initially catapulted into the limelight by celebrity acclaim, what is a vampire facial became synonymous with an avant-garde approach to cosmetic improvement. Despite the procedure's gothic moniker and mixed public reception, the medical community has been investigating and evaluating the therapeutic potential of PRP therapy with a critical eye.

Inquiries into what is a vampire facial have led to an expansion in the body of literature surrounding PRP therapy. With a focus on empirical evidence, professionals in the field of cosmetics have started to appraise the benefits and limitations of this procedure critically. This scrutiny has arisen out of a need for standardization and regulation of PRP facial practices aimed at ensuring clinical efficacy and patient safety.

Historical Sentiments Around PRP Treatments and the Vampire Facial

PRP Tube

PRP treatments, including the vampire facial, have historically been met with a blend of fascination and skepticism. Over the last decade, critics have raised questions regarding the efficacy, standardization, and safety of these procedures. The allure of celebrity endorsements initially stoked public interest, but the medical community demanded rigorous scientific validation.

The criticism was often rooted in the lack of comprehensive clinical studies to substantiate the claims of improvement in skin health. Concerns were also voiced about the variability of the techniques used to prepare and inject PRP injections, the inconsistency of formulations, and the absence of industry-wide protocols. In its nascent stages, PRP therapy became the subject of debate as practitioners tried to balance patient demands for new cosmetic treatments against the imperative for evidence-based practice. [2]

However, the dialogue around PRP treatments has evolved significantly due to growing scientific evidence. A number of studies and recent publications have started to shed light on the potential and limitations of PRP therapies.

Research detailing the correct standardization of PRP preparation, the biological mechanisms of platelets in healing, and the optimal conditions for PRP effectiveness have provided much-needed data. Reputable journals have published papers indicating improved outcomes in skin treatment with PRP when applied in controlled settings.

Peer-reviewed results are bolstering the credibility of PRP procedures and helping establish guidelines that contribute to the gradual acceptance and evaluation of the vampire facial among medical professionals [3] [4]. As a result, the sentiment within the dermatological and cosmetic surgery communities is becoming more informed and open to the potential applications of PRP treatments in the quest for skin health solutions.

Common Applications of the Vampire Facial

Despite its increasing presence in aesthetic medicine, it is important to note that the vampire facial is not an FDA-approved procedure. The U.S. Food and Drug Administration (FDA) has stringent approval processes for medical treatments, requiring extensive clinical data on safety and efficacy. PRP therapy falls into a gray area as it uses the patient’s own blood, making it a less regulated procedure than those involving drugs or medical devices. However, the lack of FDA approval does not equate to a prohibition or a definitive lack of efficacy; it simply means that standardized approval for this specific indication has not been granted.

This distinction notwithstanding, there's reason to believe in the efficacy of PRP therapy for certain applications. The rationale for PRP's use stems from its concentration of growth factors that are believed to support healthy skin cell function. Studies have reported positive outcomes in the use of PRP for facial aesthetics, including its applications in improving the appearance of fine lines, acne scars, and overall skin texture [5]. These reports, albeit in smaller-scale studies and clinical observations, have provided optimism about the potential benefits of PRP facials.

Amidst ongoing research, the popularity of PRP therapy in aesthetic medicine continues to grow. Its application is often touted alongside other non-surgical procedures as a means of supporting skin appearance. Medical professionals are presenting case studies at conferences, and anecdotal evidence from patients' positive narratives is fueling interest in the cosmetic industry. This interest is further amplified by the personalization of the treatment—as it is derived from a patient's own biological material, it is perceived as a more "natural" intervention.

Who Can Benefit From Platelet-Rich Plasma Facials?

what is vampire facial - selphyl

The ideal candidates for a vampire facial are individuals seeking improvement for specific skin conditions and who possess a baseline level of healthy skin function. These typically include people who experience signs of aging such as fine lines, a decrease in skin elasticity, or a more dull skin complexion. PRP therapy is also considered for those looking to mitigate the appearance of acne scars and seek a more even skin texture. [6]

Besides age-related concerns, patients with a history of inflammatory conditions such as rosacea could benefit from PRP facials [7], provided they are assessed and the inflammation is controlled. Individuals with hair loss concerns, specifically alopecia areata or androgenetic alopecia, might also find PRP therapy beneficial as an adjunctive treatment, as some studies suggest improvement in hair density. [8]

It is paramount that a proper patient assessment be conducted to determine suitability for PRP therapy. A thorough medical history, including current medications and lifestyle factors, should be evaluated to identify any contraindications or potential risks. Factors such as tobacco use, heavy alcohol consumption, or a history of poor wound healing may impact the effectiveness of PRP treatments.

Moreover, patients should have realistic expectations about the results of PRP therapy. It is essential to communicate that while PRP facials may support skin health, they are not a panacea for all skin conditions or signs of aging. Only after a careful assessment can a practitioner recommend PRP therapy as part of a comprehensive approach to address the individual's skin concerns.

Risks and Considerations

While PRP facials are generally considered safe due to the autologous nature of the treatment, potential risks still exist and should not be overlooked. Adverse effects may include infection at the injection site, injury to blood vessels or nerves, and pain or swelling. There is also a minor risk of an allergic reaction.

The necessity of informed consent cannot be overstated. It is crucial for patients to be thoroughly educated about the procedure, its potential benefits, and the risks involved before undergoing treatment. Understanding the limits of what PRP therapy can achieve and recognizing that outcomes may vary greatly from person to person are part of this education.

There are specific contraindications to consider; individuals with blood disorders, active infections, chronic liver disease, or those undergoing anticoagulant therapy may not be suitable candidates. Patients with a tendency toward keloids or hypertrophic scarring should also proceed with caution. Precautions must be taken to ensure the patient’s safety and optimal results, including a pre-procedure assessment and adherence to meticulous technique by the administering practitioner.

Potential Limitations and Risks

As PRP therapy garners attention across various medical and aesthetic fields, it's imperative for healthcare professionals to critically assess its limitations and the risks entailed. A thorough comprehension of these factors is pivotal for guiding informed patient consultations on PRP therapy's broad applications.

What is vampire facial - Selphyl

1. Limited Clinical Evidence

The employment of PRP therapy, while promising, is marked by a scarcity of extensive, longitudinal clinical studies. The substantiation of PRP's effectiveness across different treatment areas, along with a nuanced understanding of its potential side effects and the identification of optimally responsive patient profiles, is an active field of study.

The variability observed in treatment efficacy, influenced by the health status and specific goals of individual patients, necessitates a prudent approach from practitioners. Staying abreast of emerging research and delivering a balanced evaluation of PRP therapy's potential and safety across its various applications is essential.

2. FDA Approval

The instruments and protocols for PRP preparation and application have received clearance from regulatory entities like the U.S. Food and Drug Administration. However, specific uses of PRP therapy lack explicit FDA endorsement. As PRP is derived from a patient's own biological materials, it falls outside the purview of drug regulation, affording healthcare providers discretion in its use, tailored to the unique requirements of their patients. [9]

3. Potential for Adverse Reactions

Despite PRP's autologous origin—which significantly reduces the chances of allergic reactions or rejection—there remains a possibility for adverse effects. These can encompass localized discomfort, injection site pain, infection risk, and other procedural complications. It is therefore crucial for healthcare providers to engage in detailed discussions with patients about these risks, ensuring a well-rounded understanding of the safety aspects of PRP therapy for diverse applications.

SELPHYL® Disclaimer

Instructions for the use of SELPHYL® can be found here and here.

SELPHYL® has not been approved by the FDA for subcutaneous, submucous, or intradermal injections in aesthetic medicine, and the safety and effectiveness of SELPHYL® for these conditions have not been established.

SELPHYL® is designed to be used for the safe and rapid preparation of autologous platelet-rich plasma (PRP) from a small sample of peripheral blood at the patient's point of care. The PRP is mixed with autograft and/or allograft bone prior to application to a boney defect to improve handling characteristics.

As of the time of writing, SELPHYL® has no known serious, life-threatening, or fatal risks apart from the adverse reactions described above.

SELPHYL® Limitations, Restrictions, Cautions, and Warnings

  • Prescription only.

  • Do not use the kit if the sterile packaging is damaged or compromised.

  • Follow universal safety precautions for blood collection and sharps disposal.

  • During blood draw, failure to align and properly seat tubes in the tube holder can result in a loss of vacuum and a loss of blood draw.

  • During PRP transfer, failure to align and securely seat tubes simultaneously in assembled blood transfer device tube holders can result in a loss of vacuum and the failure of PRP to transfer to the red-top PRFM tube.

  • Do not initiate the transfer of PRP into the red-top PRFM tube until the physician is ready to complete the procedure.

  • Do not reuse.

SELPHYL® Contraindications

These are not in FDA-required labeling and are part of SELPHYL®’s clinical evaluation for EU CE requirements.

  • Direct connection to a patient’s vascular system of circulating blood volume.

  • Other health conditions and diseases may also contraindicate the use of autologous PRP, including but not limited to low platelet count, sepsis, localized infection in the treatment area, anemia, malignancy with hematologic or bony involvement, and anticoagulation therapy.


PRP facials, colloquially known as vampire facials, have stood at the intersection of fascination and scrutiny within aesthetic medicine. With indications for improving the appearance of fine lines, scars, and overall skin texture, interest in PRP therapy continues to rise. Nonetheless, the importance of managing expectations cannot be overstated, as individual results may vary and the procedure is not a cure-all.

There's a critical need for both patients and medical professionals to engage in informed discussions about the potential benefits and risks of PRP facials. All candidates must be assessed for contraindications and briefed on what the procedure entails. 

In conclusion, open dialogue and personalized consultation with healthcare providers are key to determining whether this cosmetic procedure aligns with the patient's specific aesthetic goals and physical health. Medical personnel are encouraged to review the evidence and consider patient-specific factors to ascertain if a PRP facial could be a beneficial addition to their treatment offerings.

About the author: Dr. Ali is a medical journalist and copywriter.

17 views0 comments


bottom of page